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But any goodwill is likely to have been destroyed by a leaked account of Mrs May's private Brexit dinner with Jean-Claude Juncker which took place just days before the summit in Brussels. 

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The efficacy results for patients with both ED and BPH, who received either Cialis 5 mg for once daily use or placebo (N=958) are shown in Tables 76 and 77 and Figure 8.

There are no data with the use of Cialis in pregnant women to inform any drug-associated risks for adverse developmental outcomes. In animal reproduction studies, no adverse developmental effects were observed with oral administration of tadalafil to pregnant rats or mice during organogenesis at exposures up to 66 times the maximum recommended human dose (MRHD) of 75 mg/day ( see Data).

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The placebo-subtracted mean maximal decreases in systolic blood pressure over a 67-hour period after dosing in the placebo-controlled portion of the study (part C) are shown in Table 6 and Figure 8.

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Six randomized, double-blinded, crossover clinical pharmacology studies were conducted to investigate the potential interaction of tadalafil with alpha-blocker agents in healthy male subjects [see Dosage and Administration ( ) and Warnings and Precautions ( )]. In four studies, a single oral dose of tadalafil was administered to healthy male subjects taking daily (at least 7 days duration) an oral alpha-blocker. In two studies, a daily oral alpha-blocker (at least 7 days duration) was administered to healthy male subjects taking repeated daily doses of tadalafil.

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