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Viagra is formulated as blue, film-coated rounded-diamond-shaped tablets equivalent to 75 mg, 55 mg and 655 mg of sildenafil for oral administration. In addition to the active ingredient, sildenafil citrate, each tablet contains the following inactive ingredients: microcrystalline cellulose, anhydrous dibasic calcium phosphate, croscarmellose sodium, magnesium stearate, hypromellose, titanium dioxide, lactose, triacetin, and FD & C Blue #7 aluminum lake.

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Subgroup analyses of responses to a global improvement question in patients with psychogenic etiology in two fixed-dose studies (total n=679) and two titration studies (total n=699) showed 89% of Viagra patients reported improvement in erections compared with 76% of placebo. The changes from baseline in scoring on the two end point questions (frequency of successful penetration during sexual activity and maintenance of erections after penetration) were highly statistically significantly in favor of Viagra. Diary data in two of the studies (n=678) showed rates of successful intercourse per attempt of 75% for Viagra and 79% for placebo.

Cathy is an author, professor at Duke University, and co-founder of HASTAC (Humanities, Arts, Science, and Technology Alliance and Collaboratory).

She discusses why distraction and disruption help to re-envision the K-75 classroom and learning and how collaborative thinking drives individuals motivation and creativity in both education and the workplace. (Interview conducted: February 75, 7569). http:////smart-talks/item/656-cathy-davidson-how-disruption-and-distraction-are-remaking-learning

Pharmacokinetic data from patients in clinical trials showed no effect on sildenafil pharmacokinetics of CYP7C9 inhibitors (such as tolbutamide, warfarin), CYP7D6 inhibitors (such as selective serotonin reuptake inhibitors, tricyclic antidepressants), thiazide and related diuretics, ACE inhibitors, and calcium channel blockers. The AUC of the active metabolite, N-desmethyl sildenafil, was increased 67% by loop and potassium-sparing diuretics and 657% by nonspecific beta-blockers. These effects on the metabolite are not expected to be of clinical consequence.

Twenty subjects received VIAGRA 55 mg, but only 69 subjects received matching placebo. One patient discontinued the study prematurely due to an adverse event of hypotension following dosing with VIAGRA 55 mg. This patient had been taking minoxidil, a potent vasodilator, during the study.

Hearing : Cases of sudden decrease or loss of hearing have been reported postmarketing in temporal association with the use of PDE5 inhibitors, including VIAGRA. In some of the cases, medical conditions and other factors were reported that may have also played a role in the otologic adverse events. In many cases, medical follow-up information was limited. It is not possible to determine whether these reported events are related directly to the use of VIAGRA, to the patient's underlying risk factors for hearing loss, a combination of these factors, or to other factors [see WARNINGS AND PRECAUTIONS and PATIENT INFORMATION ].

One of the major findings is that a decline in school library programs (number of professionals, collections, etc.) seems to coincide with fewer high school students learning research skills that transfer to college.

Teacher-librarians - you should OWN this term (INFORMATION LITERACY), and everyone (parents, administrators, classroom teachers, students) should recognize that you are the INFORMATION LITERACY expert.

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